August 3 1492-Columbus leaves Spain and sets sail for the East Indies.
"How the Spain-Portugal." KnowQOut. N.p., 11 Nov. 2013. Web. 20 May 2015
Aug 12 1492- Columbus lands in the new world
Elliett, Simon. "A Poets Eye." : Maio 2011. N.p., 25 Mar. 2011. Web. 20 May 2015.
Nov 8 1519-Cortes arrives,at the Aztec capital of Tenochtitlan, leading a small army of several hundred Spanish soldiers
Turnals, J. "1.4 Smallpox in Peru." ColonialDiseaseDigitalTextbook -. N.p., 19 Jan. 2010. Web. 20 May 2015.
1525-Smallpox strikes the Inca empire, killing more than 200,000 people, including the Incas' divine monarch Wayna Qhapaq.
Fenn, Elizibith A. Smallpox Epidemic. Digital image. History Today. N.p., 8 Aug. 2003. Web. 19 May 2015
Jul 8 1520-Aztecs are introduced to Smallpox by an infected soldier
Segaran, Dhevian. "Spanish Conquest." Inca Encyclopedia Block C /. N.p., 15 Jan. 2010. Web. 20 May 2015.
Mar 23, 1534-Francisco Pizarro captures the Incan capital of Cusco, finalizing Spanish conquest of the Inca empire.
Emery, Katy. "Scurvy During the Irish Famine." Bones Dont Lie. N.p., 17 Apr. 2012. Web. 20 May 2015.
1845-Potato blight destroys the Irish potato crop, leading to the deaths of more than 1 million Irish by starvation, also cause around 2 million people to emigrate.